Biomaterials and Bioprocessing 1 (Bio 1)6 ECTS
(englische Bezeichnung: Biomaterials and Bioprocessing 1)
(Prüfungsordnungsmodul: Schwerpunktfach Biomaterials and Bioprocessing 1)

Lehrveranstaltungen:

• • Biomaterials for Tissue Engineering
    (Vorlesung, 2 SWS, Aldo R. Boccaccini et al., Mo, 10:15 - 11:45, 3.71; ab 16.4.2018)
  • Immobilisation of cells and characterisation of membranes
    (Vorlesung, 2 SWS, Ruth Freitag, Block seminars will take place at Bayreuth University; dates will be organized by the MAP office)

Die allgemeine Modulbeschreibung des Prüfungsordnungsmoduls Schwerpunktfach Biomaterials and Bioprocessing 1 finden Sie hier.

Inhalt:

• Immobilisation system

• High density cell culture bioreactors

• Microcarriers – advantages and disadvantages

• Surface binding (adhesion)

• Matrix properties • DLVO Theory • Examples

• Modified surfaces

• Flocculation and Coagulation

• Van der Waals Forces and electrostatic forces • Principle of polymer flocculation • Flocculation with yeast cells

• Flocculation breakage

• Floc strength • Breakage models

• Antibody binding

• ELISA • Tumor therapy • Magnetic associated cell sorting (MACS)

• Entrapment methods

• Hollow fiber reactor • Encapsulation • Encapsulation technology • Droplet formation

• Membrane characterization

• Categories of membranes for Life Science application • Membrane materials • Membrane based processes • Applications in the biopharmaceutical industry and in medicine/medtech

Lernziele und Kompetenzen:

The lecture enables the students to achieve extensive knowledge in the field of cell cultivation including cell immobilization, cell interaction and membrane interactions. Furthermore, the lecture enables the students to analyze typical situations of application of membrane technology in the life sciences and to propose possible solutions based on understanding of both process and material aspects.

Literatur:

• Immobilised cells and enzymes. J. Woodward. IRL Press Ltd. Oxford; ISBN 0-947946-21-7

-Membranes for Life Sciences Wiley-VCH (Ed. K.-V. Peinemann, S. Pereira-Nunes)

Verwendbarkeit des Moduls / Einpassung in den Musterstudienplan:

1. Advanced Materials and Processes (Master of Science with Honours): 2. Semester
   (Po-Vers. 2014w | TechFak | Advanced Materials and Processes (Master of Science with Honours) | Masterprüfung | Schwerpunktfächer | Schwerpunktfach Biomaterials and Bioprocessing 1)

Studien-/Prüfungsleistungen:

Biomaterials for Tissue Engineering (Prüfungsnummer: 1903)

Prüfungsleistung, Hausarbeit, benotet, 3 ECTS

Anteil an der Berechnung der Modulnote: 50.0 %

Prüfungssprache: Englisch

Erstablegung: SS 2018, 1. Wdh.: WS 2018/2019

1. Prüfer:

Aldo R. Boccaccini

Immobilisation of Cells and Characterisation of Membranes (Prüfungsnummer: 1902)

Prüfungsleistung, mündliche Prüfung, Dauer (in Minuten): 30, benotet, 3 ECTS

Anteil an der Berechnung der Modulnote: 50.0 %

Prüfungssprache: Englisch

Erstablegung: SS 2018, 1. Wdh.: WS 2018/2019

1. Prüfer:

MAP-Geschäftsstelle