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Einrichtungen >> Technische Fakultät (TF) >> Department Informatik (INF) >> Lehrstuhl für Informatik 10 (Systemsimulation) >>
Iterative Solvers for Inverse Bioelectric Field Problems

Inverse problems are broadly characterized by their use of mathematical models for determining unknown system inputs, sources, parameters and/or states from observed system outputs and responses. This is the reverse of the typical, forward solution process wherein all system inputs, sources and parameters are known and mathematical models are used to predict the outputs and states.

An important class of inverse problems are those found in bioelectric field imaging. This model based analysis and visualization of bioelectric fields is of growing importance in the fields of Cardiology, Neurology and Neurosurgery. A characteristic of such problems is that because of the complex geometries, the number of degrees of freedom tends to be very large (on the order of millions) such that it is essential to create and use efficient solution techniques.

The aim of the project is to design new efficient solvers for these class of inverse problems. The research will be based on multilevel, conjugate gradient and row projection techniques. We plan to develop a mathematical analysis and to incorporate the algorithms into the SCIRun problem solving environment. SCIRun is a scientific programming environment that allows the interactive construction, debugging and steering of large-scale scientific computations. It will allow for testing the performance of the new algorithms on meshes generated from realistic patient MRI scans.

Projektleitung:
Prof. Dr. Ulrich Rüde

Beteiligte:
Prof. Dr. Constantin Popa, Prof. Dr. Christoper Johnson, Mohr, Marcus

Stichwörter:
bioelectric field; inverse problem; multilevel; projection method;

Laufzeit: 1.10.2001 - 30.9.2004

Förderer:
NATO

Mitwirkende Institutionen:
Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, U.S.A.
Faculty of Mathematics and Computer Science, Ovidius University, Constanta, Romania

Kontakt:
Rüde, Ulrich
Telefon +49 9131 85 28924, Fax +49 9131 85 28928, E-Mail: ulrich.ruede@fau.de
Publikationen
Mohr, Marcus ; Popa, Constantin ; Rüde, Ulrich: An Iterative Algorithm for Approximate Orthogonalisation of Symmetric Matrices. In: International Journal of Computer Mathematics 81 (2004), Nr. 2, S. 215-226
Pelican, Elena ; Popa, Constantin: Some Remarks on a Collocation Method for First Kind Integral Equations. Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg. 2003 (03-1). - Interner Bericht. 7 Seiten
Mohr, Marcus ; Popa, Constantin ; Rüde, Ulrich: An Iterative Algorithm for Approximate Orthogonalisation of Symmetric Matrices. Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg. 2003 (03-2). - Interner Bericht. 10 Seiten
Mohr, Marcus ; Vanrumste, Bart: A Multigrid Solver in EEG Source Analysis applying the Finite Difference Method. In: International Journal of Bioelectromagnetism 4 (2002), Nr. 2, S. 255-256
Mohr, Marcus ; Bart Vanrumste: Comparing Iterative Solvers for Linear Systems associated with the Finite Difference Discretisation of the Forward Problem in Electroencephalographic Source Analysis. In: Medical & Biological Engineering & Computing 41 (2003), Nr. 1, S. 75-84
Popa, Constantin ; Zdunek, Rafal: Kaczmarz Extended Algorithm for Tomographical Image Reconstruction from Limited-Data. Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg. 2003 (03-6). - Interner Bericht. 32 Seiten
Mohr, Marcus ; Popa, Constantin ; Rüde, Ulrich: Numerical Solution of Least-Squares Problems by a Modified Kovarik Algorithm. Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg. 2003 (03-7). - Interner Bericht. 8 Seiten
Mohr, Marcus ; Popa, Constantin ; Rüde, Ulrich: A Differential Inverse Problem from Cardiac Imaging. In: Ion, Stelian ; Marinoschi, Gabriela ; Popa, Constantin (Hrsg.) : Mathematical Modelling of Environmental Life Sciences Problems (Third Workshop on Mathematical Modelling of Environmental Life Sciences Problems Constanta, Romania 27.05.2004 - 30.05.2004). Bukarest : Editura Academiei Romane, 2004, S. 189--204. - ISBN 972-27-1113-2
Mohr, Marcus ; Wienands, Roman: Cell-centred Multigrid Revisited. In: Computing and Visualization in Science 7 (2004), Nr. 3/4, S. 129-140
Mohr, Marcus: Simulation of Bioelectric Fields: The Forward and Inverse Problem of Electro-encephalographic Source Analysis. Erlangen, FAU, Diss., 2004 (Arbeitsberichte des Instituts für Informatik Bd. 37, Nr. 6) . - 297 Seiten. ISSN 1611-4205
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